Out of ISU's 436 yards of total offense, 254 of it (58%) came on just 9 plays. Look at this 44 yard rush by Purdy. ISU scored the first TD of the day on the next play:
Iowa State lines up in 20 Personnel, Trips Right: 3 WR, 1 RB, 1 FB, 0 TE. Gladney #12, is the outside man on the right edge. His one job is to turn anything that goes outside, back to the center of the field.
Ball snaps, Gladney crashes in and allows the FB to drive him inside. You absolutely HAVE to get outside of that block and make the QB turn inside. There is no way in hell HCGMFP hasn't told this to him 100 times. The guy is a senior, on his 29th? start.
Purdy gets around Gladney, Vernon Scott #26 sees that Gladney failed to turn him inside and attempts to get outside leverage... only, he overshoots it. Daniels, #21, bit on the play action and so did Moehrig.
This was the longest play of the day for ISU. It's pretty clear to me that if Gladney turns Purdy inside, that Scott or Daniels would've cleaned it up. Even if they miss, it gives Moehrig a much better chance to keep this from going 44 yards.
I don't mean to pick on Gladney here. Several players blew their assignment every time one of these 9 plays went for over 20 yards. The only reason I'm showing this one is because it illustrates how badly the big play hurt us, when Iowa State wasn't really doing anything fancy. These types of blown assignments proved to be incredibly costly.