The disease changes over time (new variants) as does our immunity. So yeah, the science literally does change. Definitely things to learn/change from how the world handled the pandemic, but one of them is not to have the same approach the whole time. Just because an approach is right later in the pandemic doesn’t mean it is the right approach earlier in it.
Yet, Desantis opened his economy and removed mask mandates early and Florida was better for it. Because it was always the right approach.