I have a feeling that a coach like GP would absolutely hate offenses breaking from a huddle where you don't know who is going to line up where, and having very little to no time to see anything before the play. He was a master at seeing how the offense set up, and knowing what was coming.
And if you actually huddle you can call whatever you want and get into some pretty sophisticated sets. But when you're in hurry up, no huddle you're kind of limited to very basic formations and plays because its just about getting the play off before the defense is ready. But there's no rule that says if you do huddle, you have to slowly break and take your time snapping the ball.
I just think it would give defensive coaches fits to call a play in a huddle, and then get out to your spots quick and snap the ball on a quick count. In effect, the offense would be ready, and the defense wouldn't be because they wouldn't have time to figure out what was coming.